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Basic concepts of pulsatile arterial hemodynamics. Pathophysiological mechanisms Mechanical stress and the arterial wall. Arterial stiffness, wave reflections, cardiovascular risk and end-organ damage Brachial and central pulse pressure and cardiovascular risk. Large artery stiffness and cardiovascular risk; introduction to risk assessment and new strategies. Small artery elasticity index, endothelial function and cardiovascular risk. Clinical aspects of arterial stiffness and wave reflections Aging; a physical perspective. Therapeutic aspects of arterial stiffness and wave reflections Antihypertensive drug treatment and cardiovascular prevention.
Autor: O'rourke, Michael