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This book focuses on the aspects of psychopharmacology directly related to clinical care. It is organized around two major sections of the Textbook. The first section presents information by classes of drugs, focusing whole chapters on single drugs in the antidepressant, antipsychotic, and bipolar categories. For each drug within a class, data are reviewed on preclinical and clinical pharmacology, pharmacokinetics, indications, dosages, side effects and toxicology, and drug-drug interactions. Included are data on currently available drugs in the United States and medications that will almost certainly become available in the near future. The second section provides specific information about drug selection and prescription and reviews state-of-the-art therapeutic approaches to the treatment of patients with major psychiatric disorders. Also reviewed are pharmacotherapeutic approaches for special populations, such as children and adolescents, medically ill patients, and the elderly.