Confira o resumo do livro Livro G-proteins:signal Transduction And Disease – Milligan, Graeme – ISBN: 0124975151 e veja onde comprar em loja online.
G-proteins play a vital role in the regulation of transmembrane signalling cascades in a wide variety of cell types. Alterations in their expression in their expression and function are apparent in many diseases. This book addresses all the available information on modulations of the effectiveness of G-protein-mediated signal transduction in clinical disorders, ranging from alcoholism to cancers of the haemopoetic and pituitary systems. Against the context of normal signal transduction, the authors discuss whether alterations in G-protein expression and function are the consequence or a symptom of various disease states, and examine the potential of pharmacological intervention in these processes.