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This reference offers current information on the pathological alterations that occur in the biosynthesis of hormones during foetal development. Elucidating the methods of detecting diseases in the embryo using the techniques of molecular biology, this work provides exhaustive discussions of – sex differentiation abnormalities, including genetic control and the role of anti-Mullerian hormone; surfactant-associated proteins during foetal lung development; pathological problems of the placenta; the female reproductive tract immune system; alpha-foetoprotein and its implications in foetal pathology; the effects of prenatally administered sex steroids and anti-steroids on the hormonal responses of offspring; and oncogenes and growth factors during pregnancy. This work is intended for; endocrinologists; gynaecologists and obstetricians; paediatricians; pathologists; molecular and cellular biologists and biochemists; physiologists; oncologists; histologists; and upper-level undergraduate, graduate, and medical school students in these disciplines.
Autor: Pasqualini, Jorge R.