Livro online Introduction To Cellular Signal Transduction – Sitarramaya, Ari – ISBN: 0817639829 para você comprar em loja virtual. Confira preço, ofertas e descontos.
The mechanism of information transfer between cells is the subject of Signal Transduction. Until recently various aspects of signaling by hormones were studied/taught under the subject of endocrinology and signaling by neurotransmitters was the subject of neurochemistry. With the growing awareness of the many similarities between hormonal and neurotransmitter signalling, recent years have witnessed the emergence of Signal Transduction as an independent discipline covering all aspects of information transfer between cells irrespective of the nature and source of the signals. This book is designed for senio undergraduate/graduate level students interested in a basic understanding of the major participants in the cellular Signal Transduction pathways. The topics are covered with the goal of preparing the reader for a subsequent in-depth examination of specific areas of interest. The book covers most of the major topics in Signal Transduction: receptors, which recognize the signals at the cell surface; G-proteins which transduce the signals; and adenylate cyclases, guanlate cyclased, and phospholipases which generate second messengers. The discussion also focuses on ion channels, phosphodiesterases, protein kinases, phosphoprotein phosphatases and nitric oxide which participate int he cellular response to signals, the health consequences of defects in Signal Transduction proteins, and the central role Signal Transduction plays in drug abuse. The book is suitable for an introductory course in Signal Transduction as well as for self-study and review. It is recommended for biology and medical students, as well as for other science majors interested in interdisciplinary research efforts, e.g. in the pharmaceutical industry.
Autor: Sitarramaya, Ari