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The evolution of data about the HIV-Associated Lipodystrophy Syndrome has been rapid. The syndrome itself is complex and controversial. Although great progress has been made in understanding epidemiology and etiology of the syndrome, much about the syndrome remains mysterious. Each author of Lipodystrophy Syndrome in HIV was requested to provide an evidence-based discussion of a topic for which they have expertise. The approach of this volume allows the reader to develop a relatively complete snapshot of the syndrome and confront the emerging literature on the HIV-associated lipodystrophy syndrome with a critical eye.