Ler livro online, o resumo Pharmacokinetics And Metabolism In Drug Design – Smith, Dennis A. – ISBN: 3527313680. Confira preço em loja online confiável.
An understanding of pharmacokinetics is necessary to ensure that drugs that are active in vitro will also be active in the human body. The optimization of the pharmacokinetic properties of lead compounds is therefore of central importance to drug development. In this book, the authors discusses the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. They cover from the fundamental principles right up to the impact of pharmacokinetic parameters on the discovery of new drugs.