Conheça o livro e compre online. Prostaglandins & Control Of Vascular Smooth – ISBN: 3764356898.
Prostaglandins and thromboxane are well-known modulators of vessel tone and platelet activation in the cardiovascular system. Much less is known about their function as growth- modulatory agents for vascular smooth muscle cells. This volume contains chapters from a number of well-known experts on selected aspects of vascular smooth muscle function, phenotype expression and regularion of proliferation of vascular smooth muscle cells by prostaglandins and thromboxane. Specific attention is devoted to receptors and cellular signal transduction including oxidative stress, the possible interplay of these eicosanoids with other mediator systems, particularly nitric oxide and peptidergic growth factors. The possible clinical consequences of an improved understanding of how prostaglandins act for the prevention of restenosis, one of the most taxing current problems in vascular biology, are also considered. This volume can be highly recommended to all scientists, clinicians and other specialists interested in obtaining an up-to-date and comprehensive overview on the action of prostaglandins on smooth muscle cell proliferation.